Scientist / Senior Scientist: CAR immune cell specialist
Company: Cellinfinity Bio
Location: New Haven
Posted on: May 15, 2022
Scientist/Senior scientist: CAR immune cell specialist
Cellinfinity Bio is a revolutionary biotech based in New Haven,
aimed to develop new generations of effective and safe cell therapy
for cancer patients and beyond. Recently spun off from Yale
University, Cellinfinity Bio leverages proprietary, next-level gene
editing platforms for highly efficient engineering of therapeutic
immune cells, combined with proprietary directed evolution assays,
to develop the best cell therapy candidates that can overcome the
hurdles in today's cancer treatment.
Cellinfinity Bio is looking for a Scientist / Senior scientist
level position with expertise in cellular immunology and CAR immune
cell engineering. In this role, the candidate is expected to work
with the Director of Cell Therapy R&D in a matrixed environment
and perform key scientific experiments to develop Cellinfinity
Bio's products and platforms. We are looking for candidates who
enjoy working in a team and can leverage the growth opportunities
that an early startup provides. This is an exceptional opportunity
for someone who is excited about cell therapy development and
pioneering scientific efforts.
Design and perform immune cell engineering experiments, such as but
not limited to: culture of human primary cells (T, NK, iPSC etc),
CAR construction and testing, therapeutic cell engineering.
Design and perform in vitro assays, such as but not limited to:
immune cell culture and cell line development, cell cytotoxicity
assays, co-culture assays, ELISA/ELISPOT, flow cytometry and
flow-based cell sorting.
Design and perform in vivo techniques, such as adoptive cell
transfer, induction of murine tumor models, mice
injections/handling, tissue isolation, and measurement of
Develop new experimental protocols around therapeutic immune
Carefully, diligently and timely analyze and organize data.
Regularly present experimental findings to the Director of Cell
Therapy R&D, the project team, and the leadership team.
Collaborate with other biology team members.
Maintain extremely clean records of experimental schemes and
organized data at different levels.
Help draft progress reports, summaries for the IND, patent
applications and/or scientific publications.
PhD in immunology, genetics, bioengineering, cell biology, or a
related field with at least 2 years of relevant postdoctoral or
industry experience. Exceptional PhDs in the field of cell therapy,
without postdoc experience will also be considered.
Strong capability of independently designing experiments and
leading the execution of experiments.
Advanced knowledge and manipulation of immune cell-based assays,
high-dimensional flow cytometry, flow-based cell sorting, and in
Technical expertise cell engineering and mouse/human
Strong publication, patent and/or drug development record.
Excellent oral/written presentation skills.
Skills in vector design, gene editing, or NGS data analysis will be
a big plus.
Strong publication, patent and/or drug development record will be a
Cellinfinity Bio is an equal opportunity employer. The candidate
will be based in the New Haven, CT campus.
Cellinfinity Bio will provide a competitive compensation package
based on the level of the experience of the candidate. Interested
applicants should submit their resume and cover letter to
Keywords: Cellinfinity Bio, New Haven , Scientist / Senior Scientist: CAR immune cell specialist, Other , New Haven, Connecticut
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