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Senior Director, Small Molecule Research

Company: Alexion
Location: New Haven
Posted on: May 16, 2022

Job Description:

Career Opportunities: Senior Director, Small Molecule Research (25611) Requisition ID -25611 -- -Posted -10/25/2021 -- - Country (Multi Selection) (1) -- - City (Multi Selection) (1) -- -Research Some opportunities happen only once in a lifetime - like a job where you have the chance -to change lives. At Alexion, people living with rare and devastating diseases are our Guiding Star. We are driven to continuously innovate and create meaningful value in all we do to help patients and families fully live their best lives. We value the uniqueness and diversity of our employees and recognize that nurturing the diverse perspectives and strengths of our people translates into innovative breakthroughs for patients. Position Summary The role & responsibilities of the Senior Director/ Medicinal Chemistry will combine scientific decision-making and organizational leadership to advance small molecule drug discovery campaigns from hit identification through development candidate.

  • Leads and supervises a group of research scientists / associates
    • Fosters a climate of creativity, but also leads by example by bringing forth ideas to the group. Encourages others, facilitates brainstorming
    • Connects with staff members to motivate and coach and takes responsibility for staff development. Ensures appropriate level of training. Complies with all requirements of the Alexion performance management process. Provides justification for new staff and participates in hiring.
    • Establishes and manages consistent work processes for planning, evaluating progress, problem solving and prioritizing, aimed at timely, high quality scientific deliverables
    • Effectively networks within Research & Development to understand priorities and allocates effort amongst programs that aligns with these priorities
    • Ensures that the team complies with all company and departmental polices around notebook, scientific reports, QA initiatives and safety, as well as any associated mandatory training.
    • Oversees medicinal chemistry efforts in advancing small molecule discovery programs
      • Leads multidisciplinary small molecule drug discovery project teams in a fast-paced, results-driven environment
      • Design, implement and execute medicinal chemistry strategies
      • Plan and execute on resource allocation to achieve project goals
      • Provide strategic, scientific, and managerial leadership in a combination of internal and outsourced medicinal chemistry environment
      • Collaborate effectively with the leadership team and other departments and functions
      • Contribute to the overall scientific strategy and success of ALXN pipelines
      • Participates in BD diligence activities
        • Serves as an in-house expert in small molecule drug discovery and takes lead in the evaluation of in-licensing opportunities
        • Evaluates and make recommendations with respect to external research proposals regrading small molecule discovery/development candidates Qualifications
          • Doctoral degree (Ph.D.) or equivalent in Synthetic Organic Chemistry or Medicinal Chemistry 10+ years of drug discovery experience in the biotech/pharmaceutical industry, with a strong track record of scientific innovation and success in delivering clinical candidates
          • Broad background in all aspects of drug discovery, with working knowledge of ADME/PK, target coverage, pharmacology, physicochemical property-driven optimization and computational chemistry
          • A record of success in partnering with and leveraging computational chemistry for structure-based and property-based drug design of clinical candidates
          • Significant experience in leading synthetic chemistry CRO activities
          • A leader with strong organizational, interpersonal, communication and managerial expertise who motivates and inspires others to achieve corporate scientific objectives Education
            • Doctoral degree (Ph.D.) or equivalent in Synthetic Organic Chemistry or Medicinal Chemistry *LIDI-1 Alexion -is a global biopharmaceutical company focused on serving patients and families affected by rare diseases and devastating conditions through the discovery, development, and commercialization of life-changing medicines. Headquartered in Boston, Massachusetts, Alexion has offices around the globe and serves patients in more than 50 countries. Further -information about Alexion can be found at: . Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack -thereof, sex, sexual -orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, parental status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an -interactive dialogue with Alexion regarding an accommodation, please contact . Alexion participates in E-Verify. As a leading employer in our industry, Alexion offers a highly competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more. AstraZeneca completed its acquisition of Alexion, marking the creation of Alexion, AstraZeneca Rare Disease. If you're interested in career opportunities with AstraZeneca, click -here .

Keywords: Alexion, New Haven , Senior Director, Small Molecule Research, Executive , New Haven, Connecticut

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